• Carbapenem resistance determinants acquired through novel chromosomal integrations in extensively drug-resistant pseudomonas aeruginosa 

      Janice, Jessin; Agyepong, Nicholas; Owusu-Ofori, Alex; Govinden, Usha; Essack, Sabiha; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Pedersen, Torunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-17)
      Two novel bla<sub>DIM-1</sub>- or bla<SUB>IMP-1</SUB>-containing genomic islands (GIs) were discovered by whole-genome sequence analyses in four extensively drug-resistant (XDR) <i>Pseudomonas aeruginosa</i> isolates from inpatients at a tertiary hospital in Ghana. The strains were of sequence type 234 (ST234) and formed a phylogenetic clade together with ST111, which is recognized as a global ...
    • Genomic characterization of multidrug-resistant ESBL-producing Klebsiella pneumoniae isolated from a Ghanaian teaching hospital 

      Agyepong, Nicholas; Govinden, Usha; Owusu-Ofori, Alex; Amoako, Daniel Gyamfi; Allam, Mushal; Janice, Jessin; Pedersen, Torunn Annie; Sundsfjord, Arnfinn; Essack, Sabiha (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-23)
      <p><i>Objectives - </i>This study delineated the clonal lineages, antibiotic resistome and plasmid replicon types in multidrug-resistant <i>K. pneumoniae</i> isolates from a teaching hospital in Ghana. <p><i>Methods - </i>Identification and antibiotic susceptibility testing were done using the MALDI-TOF MS and Vitek-2 automated system. Genomic DNA extraction was carried out using the NucliSens ...